Robust transcriptome-wide discovery of RNA binding protein binding sites with enhanced CLIP (eCLIP)

As RNA binding proteins (RBPs) play essential roles in cellular physiology by interacting with target RNAs, binding site identification by UV-crosslinking and immunoprecipitation (CLIP) of ribonucleoprotein complexes is critical to understanding RBP function. However, current CLIP protocols are tech...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Methods
Prif Awduron: Van Nostrand, Eric L., Pratt, Gabriel A., Shishkin, Alexander A., Gelboin-Burkhart, Chelsea, Fang, Mark Y., Sundararaman, Balaji, Blue, Steven M., Nguyen, Thai B., Surka, Christine, Elkins, Keri, Stanton, Rebecca, Rigo, Frank, Guttman, Mitchell, Yeo, Gene W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887338/
https://ncbi.nlm.nih.gov/pubmed/27018577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3810
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