Robust transcriptome-wide discovery of RNA binding protein binding sites with enhanced CLIP (eCLIP)

As RNA binding proteins (RBPs) play essential roles in cellular physiology by interacting with target RNAs, binding site identification by UV-crosslinking and immunoprecipitation (CLIP) of ribonucleoprotein complexes is critical to understanding RBP function. However, current CLIP protocols are tech...

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Vydáno v:Nat Methods
Hlavní autoři: Van Nostrand, Eric L., Pratt, Gabriel A., Shishkin, Alexander A., Gelboin-Burkhart, Chelsea, Fang, Mark Y., Sundararaman, Balaji, Blue, Steven M., Nguyen, Thai B., Surka, Christine, Elkins, Keri, Stanton, Rebecca, Rigo, Frank, Guttman, Mitchell, Yeo, Gene W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887338/
https://ncbi.nlm.nih.gov/pubmed/27018577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3810
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