Robust transcriptome-wide discovery of RNA binding protein binding sites with enhanced CLIP (eCLIP)

As RNA binding proteins (RBPs) play essential roles in cellular physiology by interacting with target RNAs, binding site identification by UV-crosslinking and immunoprecipitation (CLIP) of ribonucleoprotein complexes is critical to understanding RBP function. However, current CLIP protocols are tech...

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Detalhes bibliográficos
Publicado no:Nat Methods
Main Authors: Van Nostrand, Eric L., Pratt, Gabriel A., Shishkin, Alexander A., Gelboin-Burkhart, Chelsea, Fang, Mark Y., Sundararaman, Balaji, Blue, Steven M., Nguyen, Thai B., Surka, Christine, Elkins, Keri, Stanton, Rebecca, Rigo, Frank, Guttman, Mitchell, Yeo, Gene W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887338/
https://ncbi.nlm.nih.gov/pubmed/27018577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3810
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