Subtoxic Alterations in Hepatocyte-Derived Exosomes: An Early Step in Drug-Induced Liver Injury?

Drug-induced liver injury (DILI) is a significant clinical and economic problem in the United States, yet the mechanisms that underlie DILI remain poorly understood. Recent evidence suggests that signaling molecules released by stressed hepatocytes can trigger immune responses that may be common acr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Toxicol Sci
Egile Nagusiak: Holman, Natalie S., Mosedale, Merrie, Wolf, Kristina K., LeCluyse, Edward L., Watkins, Paul B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Extracellular Vesicles and Drug-Induced Liver Injury
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880137/
https://ncbi.nlm.nih.gov/pubmed/26962055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw047
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