Combination Pod-Intravaginal Ring Delivers Antiretroviral Agents for HIV Prophylaxis: Pharmacokinetic Evaluation in an Ovine Model

Preexposure prophylaxis (PrEP) against HIV using oral regimens based on the nucleoside reverse transcriptase inhibitor tenofovir disoproxil fumarate (TDF) has been effective to various degrees in multiple clinical trials, and the CCR5 receptor antagonist maraviroc (MVC) holds potential for complemen...

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發表在:Antimicrob Agents Chemother
Main Authors: Moss, John A., Butkyavichene, Irina, Churchman, Scott A., Gunawardana, Manjula, Fanter, Rob, Miller, Christine S., Yang, Flora, Easley, Jeremiah T., Marzinke, Mark A., Hendrix, Craig W., Smith, Thomas J., Baum, Marc M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
主題:
Pharmacology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879417/
https://ncbi.nlm.nih.gov/pubmed/27067321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00391-16
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