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Novel multipurpose pod-intravaginal ring for the prevention of HIV, HSV, and unintended pregnancy: Pharmacokinetic evaluation in a macaque model

Globally, women bear an uneven burden for sexual HIV acquisition. Results from two clinical trials evaluating intravaginal rings (IVRs) delivering the antiretroviral agent dapivirine have shown that protection from HIV infection can be achieved with this modality, but high adherence is essential. Mu...

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Foilsithe in:PLoS One
Main Authors: Smith, James M., Moss, John A., Srinivasan, Priya, Butkyavichene, Irina, Gunawardana, Manjula, Fanter, Rob, Miller, Christine S., Sanchez, Debbie, Yang, Flora, Ellis, Shanon, Zhang, Jining, Marzinke, Mark A., Hendrix, Craig W., Kapoor, Amita, Baum, Marc M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628903/
https://ncbi.nlm.nih.gov/pubmed/28982161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185946
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