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Novel multipurpose pod-intravaginal ring for the prevention of HIV, HSV, and unintended pregnancy: Pharmacokinetic evaluation in a macaque model

Globally, women bear an uneven burden for sexual HIV acquisition. Results from two clinical trials evaluating intravaginal rings (IVRs) delivering the antiretroviral agent dapivirine have shown that protection from HIV infection can be achieved with this modality, but high adherence is essential. Mu...

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Publicado en:PLoS One
Autores principales: Smith, James M., Moss, John A., Srinivasan, Priya, Butkyavichene, Irina, Gunawardana, Manjula, Fanter, Rob, Miller, Christine S., Sanchez, Debbie, Yang, Flora, Ellis, Shanon, Zhang, Jining, Marzinke, Mark A., Hendrix, Craig W., Kapoor, Amita, Baum, Marc M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628903/
https://ncbi.nlm.nih.gov/pubmed/28982161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185946
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