Topical Delivery of Tenofovir Disoproxil Fumarate and Emtricitabine from Pod-Intravaginal Rings Protects Macaques from Multiple SHIV Exposures

Topical preexposure prophylaxis (PrEP) against HIV has been marginally successful in recent clinical trials with low adherence rates being a primary factor for failure. Controlled, sustained release of antiretroviral (ARV) drugs may help overcome these low adherence rates if the product is protectiv...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Srinivasan, Priya, Moss, John A., Gunawardana, Manjula, Churchman, Scott A., Yang, Flora, Dinh, Chuong T., Mitchell, James M., Zhang, Jining, Fanter, Rob, Miller, Christine S., Butkyavichene, Irina, McNicholl, Janet M., Smith, Thomas J., Baum, Marc M., Smith, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898685/
https://ncbi.nlm.nih.gov/pubmed/27275923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157061
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