Tenofovir and tenofovir disoproxil fumarate pharmacokinetics from intravaginal rings

OBJECTIVES: To compare the distribution of tenofovir in sheep vaginal lumen, tissue, and plasma following topical delivery of the antiretroviral drug from intravaginal rings, either as tenofovir or the disoproxil fumarate prodrug. DESIGN: Comparative pharmacokinetic study in sheep. METHOD: Intravagi...

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主要な著者: Moss, John A., Baum, Marc M., Malone, Amanda M., Kennedy, Sean, Kopin, Etana, Nguyen, Cali, Gilman, Josh, Butkyavichene, Irina, Willis, Robyn A., Vincent, Kathleen L., Motamedi, Massoud, Smith, Thomas J.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855348/
https://ncbi.nlm.nih.gov/pubmed/22210639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283509abb
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