Safety and Pharmacokinetics of Intravaginal Rings Delivering Tenofovir in Pig-Tailed Macaques

Antiretroviral-based microbicides applied topically to the vagina may play an important role in protecting women from HIV infection. Incorporation of the nucleoside reverse transcriptase inhibitor tenofovir (TFV) into intravaginal rings (IVRs) for sustained mucosal delivery may lead to increased mic...

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Main Authors: Moss, John A., Malone, Amanda M., Smith, Thomas J., Butkyavichene, Irina, Cortez, Cassandra, Gilman, Joshua, Kennedy, Sean, Kopin, Etana, Nguyen, Cali, Sinha, Preetha, Hendry, R. Michael, Guenthner, Patricia, Holder, Angela, Martin, Amy, McNicholl, Janet, Mitchell, James, Pau, Chou-Pong, Srinivasan, Priya, Smith, James M., Baum, Marc M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2012
נושאים:
Pharmacology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486594/
https://ncbi.nlm.nih.gov/pubmed/22964245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01198-12
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