Safety and Pharmacokinetics of Intravaginal Rings Delivering Tenofovir in Pig-Tailed Macaques

Antiretroviral-based microbicides applied topically to the vagina may play an important role in protecting women from HIV infection. Incorporation of the nucleoside reverse transcriptase inhibitor tenofovir (TFV) into intravaginal rings (IVRs) for sustained mucosal delivery may lead to increased mic...

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Bibliographic Details
Main Authors: Moss, John A., Malone, Amanda M., Smith, Thomas J., Butkyavichene, Irina, Cortez, Cassandra, Gilman, Joshua, Kennedy, Sean, Kopin, Etana, Nguyen, Cali, Sinha, Preetha, Hendry, R. Michael, Guenthner, Patricia, Holder, Angela, Martin, Amy, McNicholl, Janet, Mitchell, James, Pau, Chou-Pong, Srinivasan, Priya, Smith, James M., Baum, Marc M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486594/
https://ncbi.nlm.nih.gov/pubmed/22964245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01198-12
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