Safety and Pharmacokinetics of Intravaginal Rings Delivering Tenofovir in Pig-Tailed Macaques

Antiretroviral-based microbicides applied topically to the vagina may play an important role in protecting women from HIV infection. Incorporation of the nucleoside reverse transcriptase inhibitor tenofovir (TFV) into intravaginal rings (IVRs) for sustained mucosal delivery may lead to increased mic...

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Bibliographische Detailangaben
Hauptverfasser: Moss, John A., Malone, Amanda M., Smith, Thomas J., Butkyavichene, Irina, Cortez, Cassandra, Gilman, Joshua, Kennedy, Sean, Kopin, Etana, Nguyen, Cali, Sinha, Preetha, Hendry, R. Michael, Guenthner, Patricia, Holder, Angela, Martin, Amy, McNicholl, Janet, Mitchell, James, Pau, Chou-Pong, Srinivasan, Priya, Smith, James M., Baum, Marc M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486594/
https://ncbi.nlm.nih.gov/pubmed/22964245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01198-12
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