Safety and Pharmacokinetics of Intravaginal Rings Delivering Tenofovir in Pig-Tailed Macaques

Antiretroviral-based microbicides applied topically to the vagina may play an important role in protecting women from HIV infection. Incorporation of the nucleoside reverse transcriptase inhibitor tenofovir (TFV) into intravaginal rings (IVRs) for sustained mucosal delivery may lead to increased mic...

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Bibliografiske detaljer
Main Authors: Moss, John A., Malone, Amanda M., Smith, Thomas J., Butkyavichene, Irina, Cortez, Cassandra, Gilman, Joshua, Kennedy, Sean, Kopin, Etana, Nguyen, Cali, Sinha, Preetha, Hendry, R. Michael, Guenthner, Patricia, Holder, Angela, Martin, Amy, McNicholl, Janet, Mitchell, James, Pau, Chou-Pong, Srinivasan, Priya, Smith, James M., Baum, Marc M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486594/
https://ncbi.nlm.nih.gov/pubmed/22964245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01198-12
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