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Tenofovir and tenofovir disoproxil fumarate pharmacokinetics from intravaginal rings
OBJECTIVES: To compare the distribution of tenofovir in sheep vaginal lumen, tissue, and plasma following topical delivery of the antiretroviral drug from intravaginal rings, either as tenofovir or the disoproxil fumarate prodrug. DESIGN: Comparative pharmacokinetic study in sheep. METHOD: Intravagi...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855348/ https://ncbi.nlm.nih.gov/pubmed/22210639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283509abb |
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