Combination Pod-Intravaginal Ring Delivers Antiretroviral Agents for HIV Prophylaxis: Pharmacokinetic Evaluation in an Ovine Model

Preexposure prophylaxis (PrEP) against HIV using oral regimens based on the nucleoside reverse transcriptase inhibitor tenofovir disoproxil fumarate (TDF) has been effective to various degrees in multiple clinical trials, and the CCR5 receptor antagonist maraviroc (MVC) holds potential for complemen...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Moss, John A., Butkyavichene, Irina, Churchman, Scott A., Gunawardana, Manjula, Fanter, Rob, Miller, Christine S., Yang, Flora, Easley, Jeremiah T., Marzinke, Mark A., Hendrix, Craig W., Smith, Thomas J., Baum, Marc M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879417/
https://ncbi.nlm.nih.gov/pubmed/27067321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00391-16
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