Combination Pod-Intravaginal Ring Delivers Antiretroviral Agents for HIV Prophylaxis: Pharmacokinetic Evaluation in an Ovine Model

Preexposure prophylaxis (PrEP) against HIV using oral regimens based on the nucleoside reverse transcriptase inhibitor tenofovir disoproxil fumarate (TDF) has been effective to various degrees in multiple clinical trials, and the CCR5 receptor antagonist maraviroc (MVC) holds potential for complemen...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Moss, John A., Butkyavichene, Irina, Churchman, Scott A., Gunawardana, Manjula, Fanter, Rob, Miller, Christine S., Yang, Flora, Easley, Jeremiah T., Marzinke, Mark A., Hendrix, Craig W., Smith, Thomas J., Baum, Marc M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879417/
https://ncbi.nlm.nih.gov/pubmed/27067321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00391-16
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