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Peptidoglycan Modifications Tune the Stability and Function of the Innate Immune Receptor Nod2

Natural modifications of peptidoglycan modulate the innate immune response. Peptidoglycan derivatives activate this response via the intracellular innate immune receptor, Nod2. To probe how these modifications alter the response, a novel and eficient carbohydrate synthesis was developed to allow for...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Melnyk, James E., Mohanan, Vishnu, Schaefer, Amy K., Hou, Ching-Wen, Grimes, Catherine Leimkuhler
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878121/
https://ncbi.nlm.nih.gov/pubmed/26035228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b01607
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