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Peptidoglycan Modifications Tune the Stability and Function of the Innate Immune Receptor Nod2

Natural modifications of peptidoglycan modulate the innate immune response. Peptidoglycan derivatives activate this response via the intracellular innate immune receptor, Nod2. To probe how these modifications alter the response, a novel and eficient carbohydrate synthesis was developed to allow for...

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Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Melnyk, James E., Mohanan, Vishnu, Schaefer, Amy K., Hou, Ching-Wen, Grimes, Catherine Leimkuhler
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4878121/
https://ncbi.nlm.nih.gov/pubmed/26035228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b01607
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