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The Molecular Chaperone HSP70 Binds to and Stabilizes NOD2, an Important Protein Involved in Crohn Disease

Microbes are detected by the pathogen-associated molecular patterns through specific host pattern recognition receptors. Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is an intracellular pattern recognition receptor that recognizes fragments of the bacterial cell wall. NOD2 i...

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Bibliografiske detaljer
Main Authors: Mohanan, Vishnu, Grimes, Catherine Leimkuhler
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081938/
https://ncbi.nlm.nih.gov/pubmed/24790089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557686
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