The Molecular Chaperone HSP70 Binds to and Stabilizes NOD2, an Important Protein Involved in Crohn Disease

Por Mohanan, Vishnu, Grimes, Catherine Leimkuhler
Publicado em 2014

Identification and biological consequences of the O-GlcNAc modification of the human innate immune receptor, Nod2

Por Hou, Ching-Wen, Mohanan, Vishnu, Zachara, Natasha E, Grimes, Catherine Leimkuhler
Publicado no Glycobiology (2016)

Peptidoglycan Modifications Tune the Stability and Function of the Innate Immune Receptor Nod2

Por Melnyk, James E., Mohanan, Vishnu, Schaefer, Amy K., Hou, Ching-Wen, Grimes, Catherine Leimkuhler
Publicado no J Am Chem Soc (2015)

Crohn’s disease variants of Nod2 are stabilized by critical contact region of Hsp70

Por Schaefer, Amy K., Wastyk, Hannah C., Mohanan, Vishnu, Hou, Ching-Wen, Lauro, Mackenzie L., Melnyk, James E., Burch, Jason M., Grimes, Catherine L.
Publicado no Biochemistry (2017)

RNF166 Determines Recruitment of Adaptor Proteins During Antibacterial Autophagy

Por Heath, Robert J., Goel, Gautam, Baxt, Leigh A., Rush, Jason S., Mohanan, Vishnu, Paulus, Geraldine L.C., Jani, Vijay, Lassen, Kara G., Xavier, Ramnik J.
Publicado no Cell Rep (2016)

C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions

Por Mohanan, Vishnu, Nakata, Toru, Desch, A. Nicole, Lévesque, Chloé, Boroughs, Angela, Guzman, Gaelen, Cao, Zhifang, Creasey, Elizabeth, Yao, Junmei, Boucher, Gabrielle, Charron, Guy, Bhan, Atul K., Schenone, Monica, Carr, Steven A., Reinecker, Hans–Christian, Daly, Mark J., Rioux, John D., Lassen, Kara G., Xavier, Ramnik J.
Publicado no Science (2018)