A carregar...
Crohn’s disease variants of Nod2 are stabilized by critical contact region of Hsp70
Nod2 is a cytosolic, innate immune receptor responsible for binding to bacterial cell wall fragments such as muramyl dipeptide (MDP). Upon binding, subsequent downstream activation of the NF-κB pathway leads to an immune response. Nod2 mutations are correlated with an increased susceptibility for Cr...
Na minha lista:
| Publicado no: | Biochemistry |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5820029/ https://ncbi.nlm.nih.gov/pubmed/28792733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00470 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|