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Identification and biological consequences of the O-GlcNAc modification of the human innate immune receptor, Nod2

Nucleotide-binding oligomerization domain 2 (Nod2) is an intracellular receptor that can sense the bacterial peptidoglycan component, muramyl dipeptide. Upon activation, Nod2 induces the production of various inflammatory molecules such as cytokines and chemokines. Genetic linkage analysis identifie...

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Detalhes bibliográficos
Publicado no:Glycobiology
Main Authors: Hou, Ching-Wen, Mohanan, Vishnu, Zachara, Natasha E, Grimes, Catherine Leimkuhler
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672147/
https://ncbi.nlm.nih.gov/pubmed/26369908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwv076
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