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Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2

[Image: see text] The human gut must regulate its immune response to resident and pathogenic bacteria, numbering in the trillions. The peptidoglycan component of the bacterial cell wall is a dense and rigid structure that consists of polymeric carbohydrates and highly cross-linked peptides which off...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Schaefer, Amy K., Melnyk, James E., Baksh, Michael M., Lazor, Klare M., Finn, M. G., Grimes, Catherine Leimkuhler
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569645/
https://ncbi.nlm.nih.gov/pubmed/28708377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00469
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