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Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β

Progranulin (PGRN) has recently emerged as a key player in a subset of frontotemporal dementias (FTD). Numerous mutations in the progranulin gene have been identified in patients with familial or sporadic frontotemporal lobar degeneration (FTLD). In order to understand the molecular mechanisms by wh...

詳細記述

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書誌詳細
出版年:Protein Cell
主要な著者: Gao, Xue, Joselin, Alvin P., Wang, Lei, Kar, Amar, Ray, Payal, Bateman, Andrew, Goate, Alison M., Wu, Jane Y.
フォーマット: Artigo
言語:Inglês
出版事項: Higher Education Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875315/
https://ncbi.nlm.nih.gov/pubmed/21204008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0067-1
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