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Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β
Progranulin (PGRN) has recently emerged as a key player in a subset of frontotemporal dementias (FTD). Numerous mutations in the progranulin gene have been identified in patients with familial or sporadic frontotemporal lobar degeneration (FTLD). In order to understand the molecular mechanisms by wh...
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| 出版年: | Protein Cell |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Higher Education Press
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875315/ https://ncbi.nlm.nih.gov/pubmed/21204008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0067-1 |
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