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Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β

Progranulin (PGRN) has recently emerged as a key player in a subset of frontotemporal dementias (FTD). Numerous mutations in the progranulin gene have been identified in patients with familial or sporadic frontotemporal lobar degeneration (FTLD). In order to understand the molecular mechanisms by wh...

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Vydáno v:Protein Cell
Hlavní autoři: Gao, Xue, Joselin, Alvin P., Wang, Lei, Kar, Amar, Ray, Payal, Bateman, Andrew, Goate, Alison M., Wu, Jane Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: Higher Education Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875315/
https://ncbi.nlm.nih.gov/pubmed/21204008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0067-1
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