Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β

Progranulin (PGRN) has recently emerged as a key player in a subset of frontotemporal dementias (FTD). Numerous mutations in the progranulin gene have been identified in patients with familial or sporadic frontotemporal lobar degeneration (FTLD). In order to understand the molecular mechanisms by wh...

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Bibliografiske detaljer
Udgivet i:Protein Cell
Main Authors: Gao, Xue, Joselin, Alvin P., Wang, Lei, Kar, Amar, Ray, Payal, Bateman, Andrew, Goate, Alison M., Wu, Jane Y.
Format: Artigo
Sprog:Inglês
Udgivet: Higher Education Press 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875315/
https://ncbi.nlm.nih.gov/pubmed/21204008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0067-1
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