Caricamento...

Synthesis and Molecular Modeling of a Nitrogen Mustard DNA Interstrand Crosslink

Nitrogen Mustard Reloaded: Over 60 years after nitrogen mustards (NMs) were the first agents used to treat tumors by chemotherapy, we provide a method to generate the main DNA adduct formed by NMs and validate them using molecular dynamics simulations. We are able to provide amounts permitting exten...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Chemistry
Autori principali: Guainazzi, Angelo, Campbell, Arthur J., Angelov, Todor, Simmerling, Carlos, Schärer, Orlando D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870935/
https://ncbi.nlm.nih.gov/pubmed/20842675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201002041
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !