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Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases

DNA interstrand crosslinks (ICLs), inhibit DNA metabolism by covalently linking two strands of DNA and are formed by antitumor agents such as cisplatin and nitrogen mustards. Multiple complex repair pathways of ICLs exist in humans that share translesion synthesis (TLS) past a partially processed IC...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ho, The Vinh, Guainazzi, Angelo, Derkunt, Semsi Burak, Enoiu, Milica, Schärer, Orlando D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177197/
https://ncbi.nlm.nih.gov/pubmed/21666254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr448
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