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Bypass of DNA interstrand crosslinks by a Rev1–DNA polymerase ζ complex

DNA polymerase ζ (Pol ζ) and Rev1 are essential for the repair of DNA interstrand crosslink (ICL) damage. We have used yeast DNA polymerases η, ζ and Rev1 to study translesion synthesis (TLS) past a nitrogen mustard-based interstrand crosslink (ICL) with an 8-atom linker between the crosslinked base...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Bezalel-Buch, Rachel, Cheun, Young K, Roy, Upasana, Schärer, Orlando D, Burgers, Peter M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470978/
https://ncbi.nlm.nih.gov/pubmed/32633759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa580
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