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Involvement of Translesion Synthesis DNA Polymerases in DNA Interstrand Crosslink Repair
DNA interstrand crosslinks (ICLs) covalently join the two strands of a DNA duplex and block essential processes such as DNA replication and transcription. Several important anti-tumor drugs such as cisplatin and nitrogen mustards exert their cytotoxicity by forming ICLs. However, multiple complex pa...
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| Udgivet i: | DNA Repair (Amst) |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5524570/ https://ncbi.nlm.nih.gov/pubmed/27311543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.05.004 |
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