Caricamento...

Involvement of Translesion Synthesis DNA Polymerases in DNA Interstrand Crosslink Repair

DNA interstrand crosslinks (ICLs) covalently join the two strands of a DNA duplex and block essential processes such as DNA replication and transcription. Several important anti-tumor drugs such as cisplatin and nitrogen mustards exert their cytotoxicity by forming ICLs. However, multiple complex pa...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:DNA Repair (Amst)
Autori principali: Roy, Upasana, Schärer, Orlando D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524570/
https://ncbi.nlm.nih.gov/pubmed/27311543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.05.004
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !