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Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway
DNA interstrand crosslinks (ICLs) that are repaired in non-dividing cells must be recognized independently of replication-associated DNA unwinding. Using cell-free extracts from Xenopus eggs that support neither replication nor transcription, we establish that ICLs are recognized and processed by th...
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Publicado no: | Cell Rep |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5806701/ https://ncbi.nlm.nih.gov/pubmed/29091773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.032 |
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