Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway

DNA interstrand crosslinks (ICLs) that are repaired in non-dividing cells must be recognized independently of replication-associated DNA unwinding. Using cell-free extracts from Xenopus eggs that support neither replication nor transcription, we establish that ICLs are recognized and processed by th...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Kato, Niyo, Kawasoe, Yoshitaka, Williams, Hannah, Coates, Elena, Roy, Upasana, Shi, Yuqian, Beese, Lorena S., Schärer, Orlando D., Yan, Hong, Gottesman, Max E., Takahashi, Tatsuro S., Gautier, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806701/
https://ncbi.nlm.nih.gov/pubmed/29091773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.032
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