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Endogenous IGFBP-3 Regulates Excess Collagen Expression in Intestinal Smooth Muscle Cells of Crohn’s Disease Strictures

BACKGROUND: Stricture formation occurs in ≈30% of patients with Crohn’s disease (CD) and is a significant cause of morbidity. Strictures are characterized by intestinal smooth muscle cell hyperplasia, smooth muscle cell hypertrophy, and fibrosis due to excess net extracellular matrix production, inc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Inflamm Bowel Dis
मुख्य लेखकों: Flynn, Robert S., Mahavadi, Sunila, Murthy, Karnam S., Grider, John R., Kellum, John M., Akbari, Homayoon, Kuemmerle, John F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863983/
https://ncbi.nlm.nih.gov/pubmed/20848532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21351
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