Amelioration of excess collagen IαI, fibrosis, and smooth muscle growth in TNBS-induced colitis in IGF-I(+/−) mice

BACKGROUND & AIMS: Strictures occur in ~30% of patients with Crohn’s disease and are characterized by intestinal smooth muscle hyperplasia, hypertrophy, and fibrosis due to excess extracellular matrix production including collagen. Insulin-like Growth Factor-I (IGF-I) expression is increased in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mahavadi, Sunila, Flynn, Robert S., Grider, John R., Qiao, Liya, Murthy, Karnam S., Hazelgrove, Krystina B., Kuemmerle, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990779/
https://ncbi.nlm.nih.gov/pubmed/20722057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21437
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados