Caricamento...

Endogenous IGFBP-3 Regulates Excess Collagen Expression in Intestinal Smooth Muscle Cells of Crohn’s Disease Strictures

BACKGROUND: Stricture formation occurs in ≈30% of patients with Crohn’s disease (CD) and is a significant cause of morbidity. Strictures are characterized by intestinal smooth muscle cell hyperplasia, smooth muscle cell hypertrophy, and fibrosis due to excess net extracellular matrix production, inc...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Inflamm Bowel Dis
Autori principali: Flynn, Robert S., Mahavadi, Sunila, Murthy, Karnam S., Grider, John R., Kellum, John M., Akbari, Homayoon, Kuemmerle, John F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863983/
https://ncbi.nlm.nih.gov/pubmed/20848532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21351
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !