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Differences in the Access of Lesions to the Nucleotide Excision Repair Machinery in Nucleosomes

In nucleosomes, the access of DNA lesions to nucleotide excision repair is hindered by histone proteins. However, evidence that the nature of the DNA lesions may play a role in facilitating access is emerging, but these phenomena are not well-understood. We have used molecular dynamics simulations t...

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Dettagli Bibliografici
Pubblicato in:Biochemistry
Autori principali: Cai, Yuqin, Kropachev, Konstantin, Terzidis, Michael A., Masi, Annalisa, Chatgilialoglu, Chryssostomos, Shafirovich, Vladimir, Geacintov, Nicholas E., Broyde, Suse
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862310/
https://ncbi.nlm.nih.gov/pubmed/26091016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00564
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