Nucleotide Excision Repair and Impact of Site-Specific 5’,8-Cyclopurine and Bulky DNA Lesions on the Physical Properties of Nucleosomes

The non-bulky 5’,8-cyclopurine DNA lesions (cP) and the bulky, benzo[a]pyrene diol epoxide-derived stereoisomeric cis and trans-N(2)-guanine adducts (BPDE-dG) are good substrates of the human nucleotide excision repair (NER) mechanism. These DNA lesions were embedded at the In or Out rotational sett...

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Publicado no:Biochemistry
Main Authors: Shafirovich, Vladimir, Kolbanovskiy, Marina, Kropachev, Konstantin, Liu, Zhi, Cai, Yuquin, Terzidis, Michael A., Masi, Annalisa, Chatgilialoglu, Chryssostomos, Amin, Shantu, Dadali, Alexander, Broyde, Suse, Geacintov, Nicholas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373774/
https://ncbi.nlm.nih.gov/pubmed/30570250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01066
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