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Differences in the Access of Lesions to the Nucleotide Excision Repair Machinery in Nucleosomes

In nucleosomes, the access of DNA lesions to nucleotide excision repair is hindered by histone proteins. However, evidence that the nature of the DNA lesions may play a role in facilitating access is emerging, but these phenomena are not well-understood. We have used molecular dynamics simulations t...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Cai, Yuqin, Kropachev, Konstantin, Terzidis, Michael A., Masi, Annalisa, Chatgilialoglu, Chryssostomos, Shafirovich, Vladimir, Geacintov, Nicholas E., Broyde, Suse
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862310/
https://ncbi.nlm.nih.gov/pubmed/26091016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00564
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