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Variable impact of conformationally distinct DNA lesions on nucleosome structure and dynamics: Implications for nucleotide excision repair

The packaging of DNA in nucleosomes presents a barrier for biological transactions including replication, transcription and repair. However, despite years of research, how the DNA is freed from the histone proteins and thereby allows the molecular machines to access the DNA remains poorly understood...

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Publicado en:DNA Repair (Amst)
Autores principales: Cai, Yuqin, Geacintov, Nicholas E., Broyde, Suse
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060790/
https://ncbi.nlm.nih.gov/pubmed/32018112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102768
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