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Variable impact of conformationally distinct DNA lesions on nucleosome structure and dynamics: Implications for nucleotide excision repair

The packaging of DNA in nucleosomes presents a barrier for biological transactions including replication, transcription and repair. However, despite years of research, how the DNA is freed from the histone proteins and thereby allows the molecular machines to access the DNA remains poorly understood...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Cai, Yuqin, Geacintov, Nicholas E., Broyde, Suse
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060790/
https://ncbi.nlm.nih.gov/pubmed/32018112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102768
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