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Conformational Dynamics and Allostery in Pyruvate Kinase

Pyruvate kinase catalyzes the final step in glycolysis and is allosterically regulated to control flux through the pathway. Two models are proposed to explain how Escherichia coli pyruvate kinase type 1 is allosterically regulated: the “domain rotation model” suggests that both the domains within th...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Donovan, Katherine A., Zhu, Shaolong, Liuni, Peter, Peng, Fen, Kessans, Sarah A., Wilson, Derek J., Dobson, Renwick C. J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861489/
https://ncbi.nlm.nih.gov/pubmed/26879751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.676270
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