Conformational spread and dynamics in allostery of NMDA receptors

Allostery can be manifested as a combination of repression and activation in multidomain proteins allowing for fine tuning of regulatory mechanisms. Here we have used single molecule fluorescence resonance energy transfer (smFRET) and molecular dynamics simulations to study the mechanism of alloster...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Durham, Ryan J., Paudyal, Nabina, Carrillo, Elisa, Bhatia, Nidhi Kaur, Maclean, David M., Berka, Vladimir, Dolino, Drew M., Gorfe, Alemayehu A., Jayaraman, Vasanthi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035515/
https://ncbi.nlm.nih.gov/pubmed/32015122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910950117
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