Conformational spread and dynamics in allostery of NMDA receptors

Allostery can be manifested as a combination of repression and activation in multidomain proteins allowing for fine tuning of regulatory mechanisms. Here we have used single molecule fluorescence resonance energy transfer (smFRET) and molecular dynamics simulations to study the mechanism of alloster...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Durham, Ryan J., Paudyal, Nabina, Carrillo, Elisa, Bhatia, Nidhi Kaur, Maclean, David M., Berka, Vladimir, Dolino, Drew M., Gorfe, Alemayehu A., Jayaraman, Vasanthi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035515/
https://ncbi.nlm.nih.gov/pubmed/32015122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910950117
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