Conformational spread and dynamics in allostery of NMDA receptors

Allostery can be manifested as a combination of repression and activation in multidomain proteins allowing for fine tuning of regulatory mechanisms. Here we have used single molecule fluorescence resonance energy transfer (smFRET) and molecular dynamics simulations to study the mechanism of alloster...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Durham, Ryan J., Paudyal, Nabina, Carrillo, Elisa, Bhatia, Nidhi Kaur, Maclean, David M., Berka, Vladimir, Dolino, Drew M., Gorfe, Alemayehu A., Jayaraman, Vasanthi
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2020
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035515/
https://ncbi.nlm.nih.gov/pubmed/32015122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910950117
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