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Proton-mediated Conformational Changes in an Acid-sensing Ion Channel
Acid-sensing ion channels are cation channels activated by external protons and play roles in nociception, synaptic transmission, and the physiopathology of ischemic stroke. Using luminescence resonance energy transfer (LRET), we show that upon proton binding, there is a conformational change that i...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861639/ https://ncbi.nlm.nih.gov/pubmed/24196950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.478982 |
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