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Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive

Acid-sensing ion channels (ASICs) are trimeric cation-selective ion channels activated by protons in the physiological range. Recent reports have revealed that postsynaptically localized ASICs contribute to the excitatory postsynaptic current by responding to the transient acidification of the synap...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: MacLean, David M., Jayaraman, Vasanthi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373395/
https://ncbi.nlm.nih.gov/pubmed/28265090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620508114
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