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Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive

Acid-sensing ion channels (ASICs) are trimeric cation-selective ion channels activated by protons in the physiological range. Recent reports have revealed that postsynaptically localized ASICs contribute to the excitatory postsynaptic current by responding to the transient acidification of the synap...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: MacLean, David M., Jayaraman, Vasanthi
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373395/
https://ncbi.nlm.nih.gov/pubmed/28265090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620508114
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