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Ion and pH Sensitivity of a TMBIM Ca(2+) Channel
The anti-apoptotic transmembrane Bax inhibitor motif (TMBIM) containing protein family regulates Ca(2+) homeostasis, cell death, and diseases including cancers. The recent crystal structures of the TMBIM homolog BsYetJ reveal a conserved Asp171-Asp195 dyad that is proposed in regulating a pH-depende...
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| Publicado no: | Structure |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6560632/ https://ncbi.nlm.nih.gov/pubmed/30930064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.03.003 |
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