Multivalent benzene polyphosphate derivatives are non-Ca(2+)-mobilizing Ins(1,4,5)P(3) receptor antagonists

Por Mills, Stephen J, Luyten, Tomas, Erneux, Christophe, Parys, Jan B., Potter, Barry V. L.
Publicado em 2012

Alzheimer's disease-associated peptide Aβ(42) mobilizes ER Ca(2+) via InsP(3)R-dependent and -independent mechanisms

Por Jensen, Laura E., Bultynck, Geert, Luyten, Tomas, Amijee, Hozeefa, Bootman, Martin D., Roderick, H. Llewelyn
Publicado em 2013

mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling

Por Decuypere, Jean-Paul, Kindt, Dimphny, Luyten, Tomas, Welkenhuyzen, Kirsten, Missiaen, Ludwig, De Smedt, Humbert, Bultynck, Geert, Parys, Jan B.
Publicado em 2013

HA14-1, but not the BH3 mimetic ABT-737, causes Ca(2+) dysregulation in platelets and human cell lines

Por Akl, Haidar, Vandecaetsbeek, Ilse, Monaco, Giovanni, Kauskot, Alexandre, Luyten, Tomas, Welkenhuyzen, Kirsten, Hoylaerts, Marc, De Smedt, Humbert, Parys, Jan B., Bultynck, Geert
Publicado em 2013

Ins(1,4,5)P(3) receptor-mediated Ca(2+) signaling and autophagy induction are interrelated

Por Decuypere, Jean-Paul, Welkenhuyzen, Kirsten, Luyten, Tomas, Ponsaerts, Raf, Dewaele, Michael, Molgó, Jordi, Agostinis, Patrizia, Missiaen, Ludwig, De Smedt, Humbert, Parys, Jan B., Bultynck, Geert
Publicado em 2011

The trans-membrane domain of Bcl-2α, but not its hydrophobic cleft, is a critical determinant for efficient IP(3) receptor inhibition

Por Ivanova, Hristina, Ritaine, Abigael, Wagner, Larry, Luyten, Tomas, Shapovalov, George, Welkenhuyzen, Kirsten, Seitaj, Bruno, Monaco, Giovanni, De Smedt, Humbert, Prevarskaya, Natalia, Yule, David I., Parys, Jan B., Bultynck, Geert
Publicado no Oncotarget (2016)

The C Terminus of Bax Inhibitor-1 Forms a Ca(2+)-permeable Channel Pore

Por Bultynck, Geert, Kiviluoto, Santeri, Henke, Nadine, Ivanova, Hristina, Schneider, Lars, Rybalchenko, Volodymyr, Luyten, Tomas, Nuyts, Koen, De Borggraeve, Wim, Bezprozvanny, Ilya, Parys, Jan B., De Smedt, Humbert, Missiaen, Ludwig, Methner, Axel
Publicado em 2012

Alpha-Helical Destabilization of the Bcl-2-BH4-Domain Peptide Abolishes Its Ability to Inhibit the IP(3) Receptor

Por Monaco, Giovanni, Decrock, Elke, Nuyts, Koen, Wagner II, Larry E., Luyten, Tomas, Strelkov, Sergei V., Missiaen, Ludwig, De Borggraeve, Wim M., Leybaert, Luc, Yule, David I., De Smedt, Humbert, Parys, Jan B., Bultynck, Geert
Publicado em 2013

Human Golgi Antiapoptotic Protein Modulates Intracellular Calcium Fluxes

Por de Mattia, Fabrizio, Gubser, Caroline, van Dommelen, Michiel M.T., Visch, Henk-Jan, Distelmaier, Felix, Postigo, Antonio, Luyten, Tomas, Parys, Jan B., de Smedt, Humbert, Smith, Geoffey L., Willems, Peter H.G.M., van Kuppeveld, Frank J.M.
Publicado em 2009

The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane

Por Böhler, Philip, Stuhldreier, Fabian, Anand, Ruchika, Kondadi, Arun Kumar, Schlütermann, David, Berleth, Niklas, Deitersen, Jana, Wallot-Hieke, Nora, Wu, Wenxian, Frank, Marian, Niemann, Hendrik, Wesbuer, Elisabeth, Barbian, Andreas, Luyten, Tomas, Parys, Jan B., Weidtkamp-Peters, Stefanie, Borchardt, Andrea, Reichert, Andreas S., Peña-Blanco, Aida, García-Sáez, Ana J., Itskanov, Samuel, van der Bliek, Alexander M., Proksch, Peter, Wesselborg, Sebastian, Stork, Björn
Publicado no Cell Death Dis (2018)