mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling

Autophagy is a lysosomal degradation pathway important for cellular homeostasis and survival. Inhibition of the mammalian target of rapamycin (mTOR) is the best known trigger for autophagy stimulation. In addition, intracellular Ca(2+) regulates autophagy, but its exact role remains ambiguous. Here,...

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Detalhes bibliográficos
Main Authors: Decuypere, Jean-Paul, Kindt, Dimphny, Luyten, Tomas, Welkenhuyzen, Kirsten, Missiaen, Ludwig, De Smedt, Humbert, Bultynck, Geert, Parys, Jan B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614970/
https://ncbi.nlm.nih.gov/pubmed/23565295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061020
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