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Gating of Acid-sensitive Ion Channel-1: Release of Ca(2+) Block vs. Allosteric Mechanism
The acid-sensitive ion channels (ASICs) are a family of voltage-insensitive sodium channels activated by external protons. A previous study proposed that the mechanism underlying activation of ASIC consists of the removal of a Ca(2+) ion from the channel pore (Immke and McCleskey, 2003). In this wor...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151491/ https://ncbi.nlm.nih.gov/pubmed/16418400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509396 |
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