Conformational Dynamics and Allostery in Pyruvate Kinase

Pyruvate kinase catalyzes the final step in glycolysis and is allosterically regulated to control flux through the pathway. Two models are proposed to explain how Escherichia coli pyruvate kinase type 1 is allosterically regulated: the “domain rotation model” suggests that both the domains within th...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Donovan, Katherine A., Zhu, Shaolong, Liuni, Peter, Peng, Fen, Kessans, Sarah A., Wilson, Derek J., Dobson, Renwick C. J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Enzymology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861489/
https://ncbi.nlm.nih.gov/pubmed/26879751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.676270
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