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Conformational Dynamics and Allostery in Pyruvate Kinase

Pyruvate kinase catalyzes the final step in glycolysis and is allosterically regulated to control flux through the pathway. Two models are proposed to explain how Escherichia coli pyruvate kinase type 1 is allosterically regulated: the “domain rotation model” suggests that both the domains within th...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Donovan, Katherine A., Zhu, Shaolong, Liuni, Peter, Peng, Fen, Kessans, Sarah A., Wilson, Derek J., Dobson, Renwick C. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861489/
https://ncbi.nlm.nih.gov/pubmed/26879751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.676270
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