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Pathologic Endoplasmic Reticulum Stress Mediated by the IRE1 Pathway Contributes to Pre-insulitic Beta Cell Apoptosis in a Virus Induced Rat Model of Type 1 Diabetes
AIMS/HYPOTHESIS: We hypothesized that pathologic ER stress contributes to beta cell death during development of type 1 diabetes. In this study, we investigated the occurrence of beta cell ER stress and the signaling pathways involved during discrete stages of autoimmune diabetes progression. The vir...
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| Publicado no: | Diabetologia |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4845659/ https://ncbi.nlm.nih.gov/pubmed/24121653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-3044-4 |
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