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Endoplasmic Reticulum Stress In Beta Cells and Autoimmune Diabetes

Type 1 diabetes results from the autoimmune destruction of pancreatic β cells, leading to insulin deficiency and hyperglycemia. Although multiple attempts have been made to slow the autoimmune process using immunosuppressive or immunomodulatory agents, there are still no effective treatments that ca...

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Bibliographic Details
Published in:Curr Opin Immunol
Main Authors: Clark, Amy L., Urano, Fumihiko
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125892/
https://ncbi.nlm.nih.gov/pubmed/27718448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2016.09.006
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