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Endoplasmic reticulum stress and pancreatic beta cell death

In pancreatic β cells, the endoplasmic reticulum (ER) is an important cellular compartment for insulin biosynthesis, which accounts for half of total protein production in these cells. Protein flux through the ER must be carefully monitored to prevent dysregulation of ER homeostasis and stress. ER s...

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Bibliografiske detaljer
Main Authors: Fonseca, Sonya G., Gromada, Jesper, Urano, Fumihiko
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130122/
https://ncbi.nlm.nih.gov/pubmed/21458293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2011.02.008
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