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Endoplasmic reticulum stress and pancreatic beta cell death
In pancreatic β cells, the endoplasmic reticulum (ER) is an important cellular compartment for insulin biosynthesis, which accounts for half of total protein production in these cells. Protein flux through the ER must be carefully monitored to prevent dysregulation of ER homeostasis and stress. ER s...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3130122/ https://ncbi.nlm.nih.gov/pubmed/21458293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2011.02.008 |
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